When you wake up, you find that your browser is not loading CSS if JS is enabled in your Safari 5 . Check if it works with disabling your extensions, that means its time you periodically check to install updates of Safari extensions. ( Guess I need to enable AutoUpdate at least now ) 

SIMBL -the app which FUBARed my Safari 5

SIMBL literally FUBARed my Safari 5 (till the last minute). Having not such much experience using a Mac (aka a n00b) , I installed SIMBL for couple of extensions like lastpass for Safari couple of months back. It was not a sad moment till Safari started hanging up and not responding after installing the new extensions(which is similar to Firefox and Chrome extension list) on Safari 5 couple of weeks back. I am back on track with Safari now, though some of the websites I use often are not yet supported and probably wont be supported on Safari.

Lesson learnt : RTFM (abbr: Read The Fucking Manual)

SIMBL supports Safari for 32 bit machines is being supported on the site and the version I downloaded is not supposed to support Safari 5 (which has been released less than a month ago). 

My random checking on the Activity Monitor led me SIMBL taking as much as 400 Megs of Virt Mem which is literally a LOT and uninstalling SIMBL and starting Safari . All of it did not even take more than 1 minute for which I have wasted loads of 5mins.

TODO: Keep a note of what all you have installed and why. ( this is the toughest thing that is going to be for me or anyone. So, how can we do this ? )

Safari and SIMBL are registered trademarks or what so ever of their respective owners or creators.